Effect of acute testosterone on myocardial ischemia in men with coronary artery disease

被引：187

作者：

Webb, CM

Adamson, DL

de Zeigler, D

Collins, P

机构：

[1] Natl Heart & Lung Inst, Imperial Coll Sch Med, London SW3 6LY, England

[2] Royal Brompton Hosp, London SW3 6LY, England

[3] Columbia Labs, Paris, France

来源：

AMERICAN JOURNAL OF CARDIOLOGY | 1999年 / 83卷 / 03期

关键词：

D O I：

10.1016/S0002-9149(98)00880-7

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The effect of acute testosterone administration on exercise-induced myocardial ischemia was assessed in 14 men with coronary artery disease and low plasma testosterone concentrations in a study of randomized, double-blind, crossover design. Testosterone increased time to 1-mm ST-segment depression compared with placebo by 66 (15 to 117) seconds (p = 0.016), suggesting a beneficial effect of testosterone on myocardial ischemia in these patients.

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页码：437 / +

页数：4

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