Obesity, muscular strength, muscle composition and physical performance in an elderly population

被引:44
作者
De Stefano, F. [1 ]
Zambon, S. [1 ]
Giacometti, L. [1 ]
Sergi, G. [1 ]
Corti, M. C. [1 ]
Manzato, E. [1 ]
Busetto, L. [1 ]
机构
[1] Univ Padua, Dept Med, I-35128 Padua, Italy
基金
美国国家卫生研究院;
关键词
Obesity; physical performance; elderly; BODY-FAT; MASS; MEN; DISABILITY; AGE; WOMEN; LIFE; MOBILITY; DECLINE; HEALTH;
D O I
10.1007/s12603-015-0482-3
中图分类号
R592 [老年病学]; C [社会科学总论];
学科分类号
030301 [社会学]; 100201 [内科学];
摘要
To evaluate the association between BMI levels, muscular strength, muscle composition and physical performance in the elderly. Italians subjects from the Progetto Veneto Anziani (ProVA) study were analyzed. The ProVa was a population study focused on chronic diseases and functional limitations in Italian subjects aged a parts per thousand yen65 years living in two Northeast Italian cities. The ProVa study included 3099 subjects. ProVa participants with unknown information on BMI or disability status were excluded. The final sample was thus represented by 1.188 men, and 1.723 women. Physical performance was measured with the Short Physical Performance Battery (SPPB) and leg muscular strength with dynamometry. Fat distribution and skeletal muscle composition were measured in an abdominal single-scan magnetic resonance (MRI) in a randomly selected sample of 348 subjects. Study population was stratified by BMI classes. An association between BMI levels and SPPB was observed. Normal weight subjects showed the best SPPB scores (8.29 +/- 0.03), with significant differences compared to underweight (7.50 +/- 0.15; p < 0.001), overweight (8.12 +/- 0.02; p < 0.001), class I (7.72 +/- 0.04; p < 0.001), class II (6.67 +/- 0.09; p < 0.001) and class III obesity (5.88 +/- 0.24; p < 0.001). This pattern was not modified by adjustment for possible confounders. Compared to normal weight subjects (22.9 +/- 0.1 kg), leg muscular strength was higher in overweight (23.8 +/- 0.1; p < 0.001) and in class I obesity (24.5 +/- 0.1; p < 0.001), but it was reduced in class II (21.4 +/- 0.3; p < 0.001) and class III (19.8 +/- 0.9; p < 0.001). The association between BMI and impaired physical performance was not affected by adjustment for muscular strength. An inverse association between SPPB scores and fat infiltration in skeletal muscle was observed in patients with abdominal MRI. A poor physical performance was observed in overweight and obese elderly subjects. Leg strength was reduced only in subjects with severe obesity. Physical performance was negatively influenced by the degree of fat infiltration in skeletal muscle.
引用
收藏
页码:785 / 791
页数:7
相关论文
共 32 条
[1]
The changing relationship of obesity and disability, 1988-2004 [J].
Alley, Dawn E. ;
Chang, Virginia W. .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2007, 298 (17) :2020-2027
[2]
[Anonymous], 1998, OB PREV MAN GLOB EP
[3]
[Anonymous], 2007, COND SAL FATT RISCH
[4]
Measuring muscular strength of the lower limbs by hand-held dynamometer: A standard protocol [J].
Bandinelli, S ;
Benvenuti, E ;
Del Lungo, I ;
Baccini, M ;
Benvenuti, F ;
Di Iorio, A ;
Ferrucci, L .
AGING-CLINICAL AND EXPERIMENTAL RESEARCH, 1999, 11 (05) :287-293
[5]
Sarcopenic obesity predicts Instrumental Activities of Daily Living disability in the elderly [J].
Baumgartner, RN ;
Wayne, SJ ;
Waters, DL ;
Janssen, I ;
Gallagher, D ;
Morley, JE .
OBESITY RESEARCH, 2004, 12 (12) :1995-2004
[6]
The Effects of Weight Changes After Middle Age on the Rate of Disability in an Elderly Population Sample [J].
Busetto, Luca ;
Romanato, Giovanna ;
Zambon, Sabina ;
Calo, Elisa ;
Zanoni, Silvia ;
Corti, Maria Chiara ;
Baggio, Giovannella ;
Enzi, Giuliano ;
Crepaldi, Gaetano ;
Manzato, Enzo .
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY, 2009, 57 (06) :1015-1021
[7]
The effect of cardiovascular and osteoarticular diseases on disability in older Italian men and women: Rationale, design, and sample characteristics of the Progetto Veneto Anziani (PROVA.) study [J].
Corti, MC ;
Guralnik, JM ;
Sartori, L ;
Baggio, G ;
Manzato, E ;
Pezzotti, P ;
Barbato, G ;
Zambon, S ;
Ferrucci, L ;
Minervini, S ;
Musacchio, E ;
Crepaldi, G .
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY, 2002, 50 (09) :1535-1540
[8]
Sarcopenia: European consensus on definition and diagnosis [J].
Cruz-Jentoft, Alfonso J. ;
Baeyens, Jean Pierre ;
Bauer, Juergen M. ;
Boirie, Yves ;
Cederholm, Tommy ;
Landi, Francesco ;
Martin, Finbarr C. ;
Michel, Jean-Pierre ;
Rolland, Yves ;
Schneider, Stephane M. ;
Topinkova, Eva ;
Vandewoude, Maurits ;
Zamboni, Mauro .
AGE AND AGEING, 2010, 39 (04) :412-423
[9]
A CROSS-SECTIONAL STUDY OF MUSCLE STRENGTH AND MASS IN 45-YEAR-OLD TO 78-YR-OLD MEN AND WOMEN [J].
FRONTERA, WR ;
HUGHES, VA ;
LUTZ, KJ ;
EVANS, WJ .
JOURNAL OF APPLIED PHYSIOLOGY, 1991, 71 (02) :644-650
[10]
Obesity, regional body fat distribution, and the metabolic syndrome in older men and women [J].
Goodpaster, BH ;
Krishnaswami, S ;
Harris, TB ;
Katsiaras, A ;
Kritchevsky, SB ;
Simonsick, EM ;
Nevitt, M ;
Holvoet, P ;
Newman, AB .
ARCHIVES OF INTERNAL MEDICINE, 2005, 165 (07) :777-783