The GOA database: Gene Ontology annotation updates for 2015

被引：457

作者：

Huntley, Rachael P. ^{[1
]}

Sawford, Tony ^{[1
]}

Mutowo-Meullenet, Prudence ^{[1
]}

Shypitsyna, Aleksandra ^{[1
]}

Bonilla, Carlos ^{[1
]}

Martin, Maria J. ^{[1
]}

O'Donovan, Claire ^{[1
]}

机构：

[1] EBI, EMBL, Cambridge CB10 1SD, England

来源：

NUCLEIC ACIDS RESEARCH | 2015年 / 43卷 / D1期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1093/nar/gku1113

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

070307 [化学生物学]; 071010 [生物化学与分子生物学];

摘要：

The Gene Ontology Annotation (GOA) resource ( ext-link-type="uri" xlink:href="http://www.ebi.ac.uk/GOA" xlink:type="simple">http://www.ebi.ac.uk/GOA) provides evidence-based Gene Ontology (GO) annotations to proteins in the UniProt Knowledgebase (UniProtKB). Manual annotations provided by UniProt curators are supplemented by manual and automatic annotations from model organism databases and specialist annotation groups. GOA currently supplies 368 million GO annotations to almost 54 million proteins in more than 480 000 taxonomic groups. The resource now provides annotations to five times the number of proteins it did 4 years ago. As a member of the GO Consortium, we adhere to the most up-to-date Consortium-agreed annotation guidelines via the use of quality control checks that ensures that the GOA resource supplies high-quality functional information to proteins from a wide range of species. Annotations from GOA are freely available and are accessible through a powerful web browser as well as a variety of annotation file formats.

引用

页码：D1057 / D1063

页数：7

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