The GOA database in 2009-an integrated Gene Ontology Annotation resource

被引：416

作者：

Barrell, Daniel

Dimmer, Emily

Huntley, Rachael P.

Binns, David

O'Donovan, Claire

Apweiler, Rolf

机构：

[1] Cambridge CB10 1SD, Wellcome Trust Genome Campus, Hinxton

来源：

NUCLEIC ACIDS RESEARCH | 2009年 / 37卷

基金：

英国生物技术与生命科学研究理事会;

关键词：

UNIPROT;

D O I：

10.1093/nar/gkn803

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The Gene Ontology Annotation (GOA) project at the EBI (http://www.ebi.ac.uk/goa) provides high-quality electronic and manual associations (annotations) of Gene Ontology (GO) terms to UniProt Knowledgebase (UniProtKB) entries. Annotations created by the project are collated with annotations from external databases to provide an extensive, publicly available GO annotation resource. Currently covering over 160 000 taxa, with greater than 32 million annotations, GOA remains the largest and most comprehensive open-source contributor to the GO Consortium (GOC) project. Over the last five years, the group has augmented the number and coverage of their electronic pipelines and a number of new manual annotation projects and collaborations now further enhance this resource. A range of files facilitate the download of annotations for particular species, and GO term information and associated annotations can also be viewed and downloaded from the newly developed GOA QuickGO tool (http://www.ebi.ac.uk/QuickGO), which allows users to precisely tailor their annotation set.

引用

页码：D396 / D403

页数：8

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