Highly enantioselective phenylacetylene addition to aldehydes catalyzed by a chiral N,O-ferrocene ligand

被引：62

作者：

Li, M ^{[1
]}

Zhu, XZ ^{[1
]}

Yuan, K ^{[1
]}

Cao, BX ^{[1
]}

Hou, XL ^{[1
]}

机构：

[1] Chinese Acad Sci, Shanghai Inst Organ Chem, State Key Lab Organometall Chem, Shanghai 200032, Peoples R China

来源：

TETRAHEDRON-ASYMMETRY | 2004年 / 15卷 / 02期

基金：

中国国家自然科学基金;

关键词：

ferrocene ligand; alkynylation; aldehyde; organozinc reagent; asymmetric addition;

D O I：

10.1016/j.tetasy.2003.12.002

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Ferrocenyl oxazoline alcohols are found to be effective in catalyzing the addition reaction of an alkynylzinc reagent to aromatic and aliphatic aldehydes with up to 93% ee of the thus produced chiral propargyl alcohols. (C) 2003 Elsevier Ltd. All rights reserved.

引用

页码：219 / 222

页数：4

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