Properties of retinoids - Structure, handling, and preparation

被引:53
作者
Barua, AB [1 ]
Furr, HC [1 ]
机构
[1] Iowa State Univ, Dept Biochem & Biophys, Ames, IA 50011 USA
关键词
retinoids; retinoic acid; retinol; properties; storage; handling; derivatization;
D O I
10.1007/BF02760863
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 [生物化学与分子生物学]; 081704 [应用化学];
摘要
Retinoids are unstable compounds being readily oxidized and/or isomerized to altered compounds, especially in the presence of oxidants including air, light, and excessive heat. They are labile toward strong acids : and solvents that have dissolved oxygen or peroxides. In this review, procedures for handling and storage of retinoids and biological samples containing them have been described. The physical and chemical properties of retinoids have been reported. Simplified procedures for derivatizations and purification, and methods far quantitation of retinoids have been presented.
引用
收藏
页码:167 / 182
页数:16
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