Biocompatible carbon nanotubes generated by functionalization with glycodendrimers

被引：140

作者：

Wu, Peng ^{[1
]}

Chen, Xing ^{[1
]}

Hu, Nancy ^{[1
]}

Tam, Un Chong ^{[1
]}

Blixt, Ola ^{[5
]}

Zettl, Alex ^{[4
,6
]}

Bertozzi, Carolyn R. ^{[1
,2
,3
]}

机构：

[1] Univ Calif Berkeley, Dept Chem, Berkeley, CA 94720 USA

[2] Univ Calif Berkeley, Dept Mol & Cell Biol, Berkeley, CA 94720 USA

[3] Univ Calif Berkeley, Howard Hughes Med Inst, Berkeley, CA 94720 USA

[4] Univ Calif Berkeley, Lawrence Berkeley Lab, Div Mat Sci, Berkeley, CA 94720 USA

[5] Scripps Res Inst, Carbohydrate Synth & Prot Express Core D Consorti, La Jolla, CA 92037 USA

[6] Univ Calif Berkeley, Dept Phys, Berkeley, CA 94720 USA

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2008年 / 47卷 / 27期

关键词：

biomimetic synthesis; carbon; dendrimers; glycoconjugates; nanotubes;

D O I：

10.1002/anie.200705363

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Protective coatings: Glycodendrimers can function as homogeneous bioactive coatings that mitigate the cytotoxicity of single-walled carbon nanotubes (SWNTs). The bifunctional glycodendrimers (see picture) have peripheral carbohydrate units and a pyrene tail capable of binding SWNT surfaces through π-π interaction. Cells cultured with glycodendrimer-coated SWNTs proliferate at the same rate as untreated cells. (Chemical Equation Presented) © 2008 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

收藏

页码：5022 / 5025

页数：4

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