ELECTRICAL CONDUCTION BLOCK IN LARGE NERVES: HIGH-FREQUENCY CURRENT DELIVERY IN THE NONHUMAN PRIMATE

被引:34
作者
Ackermann, D. Michael, Jr. [1 ,2 ]
Ethier, Christian [3 ]
Foldes, Emily L. [2 ]
Oby, Emily R. [3 ]
Tyler, Dustin [2 ]
Bauman, Matt [3 ]
Bhadra, Niloy [1 ,2 ]
Miller, Lee [3 ]
Kilgore, Kevin L. [1 ,2 ,4 ]
机构
[1] Cleveland FES Ctr, Cleveland, OH 44109 USA
[2] Case Western Reserve Univ, Cleveland, OH 44106 USA
[3] Northwestern Univ, Evanston, IL USA
[4] Louis Stokes Vet Affairs Med Ctr, Cleveland, OH USA
关键词
conduction block; high-frequency alternating current (HFAC); large diameter; peripheral nerve; primate; PUDENDAL NERVE; ALTERNATING CURRENTS; STIMULATION; ELECTRODE;
D O I
10.1002/mus.22037
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Recent studies have made significant progress toward the clinical implementation of high-frequency conduction block (HFB) of peripheral nerves. However, these studies were performed in small nerves, and questions remain regarding the nature of HFB in large-diameter nerves. This study in nonhuman primates shows reliable conduction block in large-diameter nerves (up to 4.1 mm) with relatively low-threshold current amplitude and only moderate nerve discharge prior to the onset of block. Muscle Nerve 43: 897-899, 2011
引用
收藏
页码:897 / 899
页数:3
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