CONDUCTION BLOCK OF PERIPHERAL NERVE USING HIGH-FREQUENCY ALTERNATING CURRENTS DELIVERED THROUGH AN INTRAFASCICULAR ELECTRODE

被引：31

作者：

Ackermann, D. Michael, Jr. ^{[1
]}

Foldes, Emily L. ^{[1
]}

Bhadra, Niloy ^{[1
,2
]}

Kilgore, Kevin L. ^{[1
,2
,3
]}

机构：

[1] Case Western Reserve Univ, Cleveland, OH 44106 USA

[2] Cleveland FES Ctr, MetroHlth Med Ctr, Cleveland, OH 44109 USA

[3] Louis Stokes Vet Affairs Med Ctr, Cleveland, OH USA

来源：

MUSCLE & NERVE | 2010年 / 41卷 / 01期

关键词：

nerve block; high frequency; intrafascicular; stimulation; electrode; CAT SCIATIC-NERVE; SELECTIVE STIMULATION; ARRAY; MICROELECTRODES; SIMULATION; FIBERS; UNITS;

D O I：

10.1002/mus.21496

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Many diseases are characterized by undesired or pathological neural activity. The local delivery of high-frequency currents has been shown to be an effective method for blocking neural conduction in peripheral nerves and may provide a therapy for these conditions. To date, all studies of high-frequency conduction block have utilized extraneural (cuff) electrodes to achieve conduction block. In this study we show that high-frequency conduction block is feasible using intrafascicular electrodes. Muscle Nerve 41: 117-119, 2010

引用

页码：117 / 119

页数：3

共 23 条

[1] High-frequency electrical conduction block of mammalian peripheral motor nerve [J].

Bhadra, N ;

Kilgore, KL .

MUSCLE & NERVE, 2005, 32 (06) :782-790

[2]

Bhadra N, 2007, J COMPUT NEUROSCI, V22, P313, DOI [10.1007/s10827-006-0015-5, 10.1007/S10827-006-0015-5]

[3] ACUTE AND CHRONIC IMPLANTATION OF COILED WIRE INTRANEURAL ELECTRODES DURING CYCLICAL ELECTRICAL-STIMULATION [J].

BOWMAN, BR ;

ERICKSON, RC .

ANNALS OF BIOMEDICAL ENGINEERING, 1985, 13 (01) :75-93

[4]

BOWMAN BR, 1986, APPL NEUROPHYSIOL, V49, P121

[5] Long-term stimulation and recording with a penetrating microelectrode array in cat sciatic nerve [J].

Branner, A ;

Stein, RB ;

Fernandez, E ;

Aoyagi, Y ;

Normann, RA .

IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING, 2004, 51 (01) :146-157

[6] A multielectrode array for intrafascicular recording and stimulation in sciatic nerve of cats [J].

Branner, A ;

Normann, RA .

BRAIN RESEARCH BULLETIN, 2000, 51 (04) :293-306

[7] Selective stimulation of cat sciatic nerve using an array of varying-length microelectrodes [J].

Branner, A ;

Stein, RB ;

Normann, RA .

JOURNAL OF NEUROPHYSIOLOGY, 2001, 85 (04) :1585-1594

[8] Microelectrode recordings from human peripheral nerves (microneurography) [J].

Hagbarth, KE .

MUSCLE & NERVE, 2002, :S28-S35

[9] Nerve conduction block utilising high-frequency alternating current [J].

Kilgore, KL ;

Bhadra, N .

MEDICAL & BIOLOGICAL ENGINEERING & COMPUTING, 2004, 42 (03) :394-406

[10] Fabrication and characteristics of an implantable, polymer-based, intrafascicular electrode [J].

Lawrence, SM ;

Dhillon, GS ;

Horch, KW .

JOURNAL OF NEUROSCIENCE METHODS, 2003, 131 (1-2) :9-26

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