Membrane targeting: What a difference a G makes

被引:22
作者
Cullen, PJ [1 ]
Chardin, P
机构
[1] Univ Bristol, Dept Biochem, Bristol BS8 1TD, Avon, England
[2] CNRS, Inst Pharmacol, F-06560 Sophia Antipolis, France
关键词
D O I
10.1016/S0960-9822(00)00818-6
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Pleckstrin homology domains are modular domains that direct membrane targeting of their host proteins by binding to polyphosphoinositides; recent results have increased our appreciation of how some of these domains actually bind 3-phosphoinositides, and along the way thrown up some unexpected observations.
引用
收藏
页码:R876 / R878
页数:3
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