Total synthesis of marine bisindole alkaloids, (+)-hamacanthins A, B and (-)-antipode of cis-dihydrohamacanthin B

被引：60

作者：

Kouko, T ^{[1
]}

Matsumura, K ^{[1
]}

Kawasaki, T ^{[1
]}

机构：

[1] Meiji Pharmaceut Univ, Tokyo 2048588, Japan

来源：

TETRAHEDRON | 2005年 / 61卷 / 09期

关键词：

bromoindole; indolylglycinol; oxazolidin-2-one; absolute configuration;

D O I：

10.1016/j.tet.2005.01.058

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The total synthesis of the marine bisindole alkaloids, (+)-hamacanthins A (2a) and B (2b), and (-)-antipode of cis-dihydrohamacanthin B (2e) was achieved by transamidation-cyclization of N-(2-aminoethyl)-2-oxoethanamide 18 derived from (S)-indolylglycinol 10. (C) 2005 Elsevier Ltd. All rights reserved.

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页码：2309 / 2318

页数：10

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