Bacterial chromatin

被引：111

作者：

Travers, A

Muskhelishvili, G

机构：

[1] Int Jacobs Univ Bremen, D-28759 Bremen, Germany

[2] MRC, Mol Biol Lab, Cambridge CB2 2QH, England

来源：

CURRENT OPINION IN GENETICS & DEVELOPMENT | 2005年 / 15卷 / 05期

关键词：

D O I：

10.1016/j.gde.2005.08.006

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Recent studies have revealed that the bacterial nucleoid is a dynamic entity that alters its overall structure in response to changes in both growth rate and growth phase. These structural changes are correlated with, and might be driven by, changes in the distribution and utilization of DNA supercoiling. In turn, these parameters in addition to the delimitation of topological domains are dependent both on the relative proportions of the abundant nucleoid-associated proteins and on transcriptional activity. The domain structure itself is dynamic.

引用

收藏

页码：507 / 514

页数：8

相关论文

共 46 条

[31] FIS modulates growth phase-dependent topological transitions of DNA in Escherichia coli [J].

Schneider, R ;

Travers, A ;

Muskhelishvili, G .

MOLECULAR MICROBIOLOGY, 1997, 26 (03) :519-530

[32] An architectural role of the Escherichia coli chromatin protein FIS in organising DNA [J].

Schneider, R ;

Lurz, R ;

Lüder, G ;

Tolksdorf, C ;

Travers, A ;

Muskhelishvili, G .

NUCLEIC ACIDS RESEARCH, 2001, 29 (24) :5107-5114

[33] The expression of the Escherichia coli fis gene is strongly dependent on the superhelical density of DNA [J].

Schneider, R ;

Travers, A ;

Muskhelishvili, G .

MOLECULAR MICROBIOLOGY, 2000, 38 (01) :167-175

[34] CHROMOSOMES IN LIVING ESCHERICHIA-COLI-CELLS ARE SEGREGATED INTO DOMAINS OF SUPERCOILING [J].

SINDEN, RR ;

PETTIJOHN, DE .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1981, 78 (01) :224-228

[35] Bacillus subtilis actin-like protein MreB influences the positioning of the replication machinery and requires membrane proteins MreC/D and other actin-like proteins for proper localization -: art. no. 10 [J].

Soufo, HJD ;

Graumann, PL .

BMC CELL BIOLOGY, 2005, 6 (1)

[36] Gyrase and Topo IV modulate chromosome domain size in vivo [J].

Staczek, P ;

Higgins, NP .

MOLECULAR MICROBIOLOGY, 1998, 29 (06) :1435-1448

[37] Measuring chromosome dynamics on different time scales using resolvases with varying half-lives [J].

Stein, RA ;

Deng, S ;

Higgins, NP .

MOLECULAR MICROBIOLOGY, 2005, 56 (04) :1049-1061

[38] Flexible DNA bending in HU-DNA cocrystal structures [J].

Swinger, KK ;

Lemberg, KM ;

Zhang, Y ;

Rice, PA .

EMBO JOURNAL, 2003, 22 (14) :3749-3760

[39] The structure and function of the bacterial chromosome [J].

Thanbichler, M ;

Viollier, PH ;

Shapiro, L .

CURRENT OPINION IN GENETICS & DEVELOPMENT, 2005, 15 (02) :153-162

[40] DNA supercoiling - A global transcriptional regulator for enterobacterial growth? [J].

Travers, A ;

Muskhelishvili, G .

NATURE REVIEWS MICROBIOLOGY, 2005, 3 (02) :157-169

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