Circulating endothelial progenitor cells

被引:60
作者
Garmy-Susini, B [1 ]
Varner, JA [1 ]
机构
[1] Univ Calif San Diego, John & Rebecca Moores Comprehens Canc Ctr, La Jolla, CA 92093 USA
关键词
angiogenesis; stem cell; endothelial progenitor cell; CD34(+) cell; monocyte;
D O I
10.1038/sj.bjc.6602808
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Angiogenesis research investigates the formation of new blood vessels in wound healing, tumour growth and embryonic development. Circulating, bone marrow-derived endothelial progenitor cells (EPCs) were first described 8 years ago, yet the exact nature of these endothelial precursor cells remains unclear. The contributions of circulating EPCs to angiogenesis in tumours, ischaemic injury and other diseases as well as their usefulness in the repair of wounded hearts and limbs remain under intense investigation.
引用
收藏
页码:855 / 858
页数:4
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