Applications of peptide arrays prepared by the SPOT-technology

被引：196

作者：

Reineke, U

Volkmer-Engert, R

Schneider-Mergener, J

机构：

[1] Jerini AG, D-12489 Berlin, Germany

[2] Humboldt Univ, Klinikum Charite, D-10117 Berlin, Germany

来源：

CURRENT OPINION IN BIOTECHNOLOGY | 2001年 / 12卷 / 01期

关键词：

D O I：

10.1016/S0958-1669(00)00178-6

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

The growing range of applications for peptide arrays synthesized on coherent membranes by the SPOT-synthesis method proves they have emerged as a powerful proteomics technique to study molecular recognition events and identify biologically active peptides. Several developments, such as the introduction of novel polymeric surfaces, linkers, synthesis/cleavage strategies and detection methods, are facilitating an increasing spectrum of accessible compounds and applications in biological or pharmaceutical research.

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页码：59 / 64

页数：6

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