Applications of peptide arrays prepared by the SPOT-technology

被引:196
作者
Reineke, U
Volkmer-Engert, R
Schneider-Mergener, J
机构
[1] Jerini AG, D-12489 Berlin, Germany
[2] Humboldt Univ, Klinikum Charite, D-10117 Berlin, Germany
关键词
D O I
10.1016/S0958-1669(00)00178-6
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
The growing range of applications for peptide arrays synthesized on coherent membranes by the SPOT-synthesis method proves they have emerged as a powerful proteomics technique to study molecular recognition events and identify biologically active peptides. Several developments, such as the introduction of novel polymeric surfaces, linkers, synthesis/cleavage strategies and detection methods, are facilitating an increasing spectrum of accessible compounds and applications in biological or pharmaceutical research.
引用
收藏
页码:59 / 64
页数:6
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