Benzotriazol-1-yl-sulfonyl Azide for Diazotransfer and Preparation of Azidoacylbenzotriazoles

被引：52

作者：

Katritzky, Alan R. ^{[1
]}

El Khatib, Mirna ^{[1
]}

Bol'shakov, Oleg ^{[1
]}

Khelashvili, Levan ^{[1
]}

Steel, Peter J. ^{[2
]}

机构：

[1] Univ Florida, Dept Chem, Ctr Heterocycl Cpds, Gainesville, FL 32611 USA

[2] Univ Canterbury, Dept Chem, Christchurch 1, New Zealand

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2010年 / 75卷 / 19期

关键词：

C-H ACTIVATION; DIAZO-TRANSFER; ARYL AZIDES; AMINO-ACIDS; BENZENESULFONYL AZIDE; ORGANIC-SYNTHESIS; EFFICIENT; REAGENT; ACYLBENZOTRIAZOLES; DIHYDROXYLATION;

D O I：

10.1021/jo101296s

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Benzotriazol-1-yl-sulfonyl azide, a new crystalline, stable, and easily available diazotransfer reagent provides N-(alpha-azidoacyl)benzotriazoles convenient for N-, O-, C- and S-acylations. The efficient syntheses of various amides, azido protected peptides, esters, ketones and thioesters is reported together with a wide range of azides (including alpha-azido acids from alpha- amino acids in partially aqueous conditions) and diazo compounds.

引用

页码：6532 / 6539

页数：8

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