Treatment of chronic inflammatory demyelinating polyneuropathy with cyclosporin-A

被引：55

作者：

Mahattanakul, W

Crawford, TO

Griffin, JW

Goldstein, JM

Cornblath, DR

机构：

[1] JOHNS HOPKINS UNIV,SCH MED,DEPT NEUROL,BALTIMORE,MD

[2] YALE UNIV,SCH MED,NEW HAVEN,CT

来源：

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY | 1996年 / 60卷 / 02期

关键词：

cyclosporin-A; inflammatory demyelinating polyneuropathy;

D O I：

10.1136/jnnp.60.2.185

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Chronic inflammatory demyelinating polyneuropathy (CIDP) is an immune mediated polyneuropathy for which there are effective therapies. However, not all patients improve with these treatments. Eight patients with CIDP, two with IgG monoclonal gammopathies, were treated with cyclosporin-A (3 to 5 mg/kg/day). In three, this treatment was successful. It was unsuccessful in four patients who were resistant to other treatments and in one who had initially received cyclosporin-A. There were no serious side effects. In selected patients with CIDP, cyclosporin-A is a potentially useful treatment.

引用

页码：185 / 187

页数：5

共 9 条

[1]

CORNBLATH DR, 1991, NEUROLOGY, V41, P617

[2]

DYCK PJ, 1993, PERIPHERAL NEUROPATH, P1498

[3] THE TREATMENT OF CHRONIC RELAPSING AND CHRONIC PROGRESSIVE IDIOPATHIC INFLAMMATORY POLYNEUROPATHY BY PLASMA-EXCHANGE [J].