Metallic barcodes for multiplexed bioassays

被引：41

作者：

Brunker, Sarah E. ^{[1
]}

Cederquist, Kristin B. ^{[1
]}

Keating, Christine D. ^{[1
]}

机构：

[1] Penn State Univ, Dept Chem, University Pk, PA 16802 USA

来源：

NANOMEDICINE | 2007年 / 2卷 / 05期

关键词：

barcoded nanowires; bioconjugate; biosensors; cancer detection; encoded particles; fluorescence; nanotechnology;

D O I：

10.2217/17435889.2.5.695

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Both detection and postdiagnosis monitoring are critical for cancer isolation and treatment. Particle-based sensing strategies could help to address these medical needs. This review describes barcoded metallic nanowires as particle scaffolds for multiplexed detection of antigens or nucleic acids. Barcode patterns are compositionally encoded as stripes of gold and silver metal along the nanowire length during fabrication by templated electrodeposition. Particle identification is accomplished using reflectance optical microscopy and can be coupled with fluorescence readout of antigen- or nucleic acid-binding events. Several approaches to multiplexed biodetection based on barcoded nanowires will be described and the potential for these particles in cancer detection will be discussed.

引用

页码：695 / 710

页数：16

共 62 条

[1] NANOWIRES FORMED IN ANODIC OXIDE NANOTEMPLATES [J].

ALMAWLAWI, D ;

LIU, CZ ;

MOSKOVITS, M .

JOURNAL OF MATERIALS RESEARCH, 1994, 9 (04) :1014-1018

[2]

Andreadis J D, 2000, Nucleic Acids Res, V28, pe5, DOI 10.1093/nar/28.2.e5

[3] Toward larger chemical libraries: Encoding with fluorescent colloids in combinatorial chemistry [J].

Battersby, BJ ;

Bryant, D ;

Meutermans, W ;

Matthews, D ;

Smythe, ML ;

Trau, M .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2000, 122 (09) :2138-2139

[4]

Bidart JM, 1999, CLIN CHEM, V45, P1695

[5] Encoding microcarriers by spatial selective photobleaching [J].

Braeckmans, K ;

De Smedt, SC ;

Roelant, C ;

Leblans, M ;

Pauwels, R ;

Demeester, J .

NATURE MATERIALS, 2003, 2 (03) :169-173

[6] Nanowire nanosensors for highly sensitive and selective detection of biological and chemical species [J].

Cui, Y ;

Wei, QQ ;

Park, HK ;

Lieber, CM .

SCIENCE, 2001, 293 (5533) :1289-1292

[7] Rare earth-doped glass microbarcodes [J].

Dejneka, MJ ;

Streltsov, A ;

Pal, S ;

Frutos, AG ;

Powell, CL ;

Yost, K ;

Yuen, PK ;

Müller, U ;

Lahiri, J .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2003, 100 (02) :389-393

[8] Temperature-programmed assembly of DNA:Au nanoparticle bioconjugates [J].

Dillenback, LM ;

Goodrich, GP ;

Keating, CD .

NANO LETTERS, 2006, 6 (01) :16-23

[9] Qdot nanobarcodes for multiplexed gene expression analysis [J].

Eastman, P. Scott ;

Ruan, Weiming ;

Doctolero, Michael ;

Nuttall, Rachel ;

De Feo, Gianfranco ;

Park, Jennifer S. ;

Chu, Julia S. F. ;

Cooke, Patrick ;

Gray, Joe W. ;

Li, Song ;

Chen, Fanqing Frank .

NANO LETTERS, 2006, 6 (05) :1059-1064

[10] The case for early detection [J].

Etzioni, R ;

Urban, N ;

Ramsey, S ;

McIntosh, M ;

Schwartz, S ;

Reid, B ;

Radich, J ;

Anderson, G ;

Hartwell, L .

NATURE REVIEWS CANCER, 2003, 3 (04) :243-252

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