Methylation meets genomics

被引：56

作者：

Feinberg, AP ^{[1
]}

机构：

[1] Johns Hopkins Univ, Sch Med, Inst Med Genet, Baltimore, MD 21205 USA

来源：

NATURE GENETICS | 2001年 / 27卷 / 01期

关键词：

D O I：

10.1038/83825

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

The methylome-a neologism that describes the complete set of DNA methylation modifications of a cell-has its own life cycle, and alterations in the methylome may be linked to aging and cancer, as well as polymorphic variation in populations. A study of the methylome in embryonic fibroblasts further underscores the potent effect of p53 expression.

引用

页码：9 / 10

页数：2

共 16 条

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