Developmental biology - A twist on embryonic signalling

被引：27

作者：

Harland, RM ^{[1
]}

机构：

[1] Univ Calif Berkeley, Dept Mol & Cell Biol, Berkeley, CA 94720 USA

来源：

NATURE | 2001年 / 410卷 / 6827期

关键词：

D O I：

10.1038/35068657

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Gradients of signalling proteins control the formation of different tissues during animal development. A controversial model for how one such gradient is produced now receives more experimental support.

引用

页码：423 / 424

页数：3

共 13 条

[1] Local inhibition and long-range enhancement of Dpp signal transduction by Sog
Ashe, HL
Levine, M
[J]. NATURE, 1999, 398 (6726) : 427 - 431
[2] Noggin, cartilage morphogenesis, and joint formation in the mammalian skeleton
Brunet, LJ
McMahon, JA
McMahon, AP
Harland, RM
[J]. SCIENCE, 1998, 280 (5368) : 1455 - 1457
[3] Twisted gastrulation can function as a BMP antagonist
Chang, CB
Holtzman, DA
Chau, S
Chickering, T
Woolf, EA
Holmgren, LM
Bodorova, J
Gearing, DP
Holmes, WE
Brivanlou, AH
[J]. NATURE, 2001, 410 (6827) : 483 - 487
[4] Dorfman R, 2001, DEVELOPMENT, V128, P965
[5] Production of a DPP activity gradient in the early Drosophila embryo through the opposing actions of the SOG and TLD proteins
Marques, G
Musacchio, M
Shimell, MJ
WunnenbergStapleton, K
Cho, KWY
OConnor, MB
[J]. CELL, 1997, 91 (03) : 417 - 426
[6] The evolutionarily conserved BMP-binding protein Twisted gastrulation promotes BMP signalling
Oelgeschläger, M
Larraín, J
Geissert, D
De Robertis, EM
[J]. NATURE, 2000, 405 (6788) : 757 - 763
[7] Dorsoventral patterning in xenopus: Inhibition of ventral signals by direct binding of Chordin to BMP-4
Piccolo, S
Sasai, Y
Lu, B
DeRobertis, EM
[J]. CELL, 1996, 86 (04) : 589 - 598
[8] Cleavage of chordin by Xolloid metalloprotease suggests a role for proteolytic processing in the regulation of Spemann organizer activity
Piccolo, S
Agius, E
Lu, B
Goodman, S
Dale, L
DeRobertis, EM
[J]. CELL, 1997, 91 (03) : 407 - 416
[9] Morphogen gradients - New insights from DPP
Podos, SD
Ferguson, EL
[J]. TRENDS IN GENETICS, 1999, 15 (10) : 396 - 402
[10] Twisted gastrulation is a conserved extracellular BMP antagonist
Ross, JJ
Shimmi, O
Vilmos, P
Petryk, A
Kim, H
Gaudenz, K
Hermanson, S
Ekker, SC
O'Connor, MB
Marsh, JL
[J]. NATURE, 2001, 410 (6827) : 479 - 483

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