A copper cofactor for the ethylene receptor ETR1 from Arabidopsis

被引：496

作者：

Rodriguez, FI ^{[1
]}

Esch, JJ ^{[1
]}

Hall, AE ^{[1
]}

Binder, BM ^{[1
]}

Schaller, GE ^{[1
]}

Bleecker, AB ^{[1
]}

机构：

[1] Univ Wisconsin, Dept Bot, Madison, WI 53706 USA

来源：

SCIENCE | 1999年 / 283卷 / 5404期

关键词：

D O I：

10.1126/science.283.5404.996

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The ETR1 receptor from Arabidopsis binds the gaseous hormone ethylene, A copper ion associated with the ethylene-binding domain is required for high-affinity ethylene-binding activity. A missense mutation in the domain that renders the plant insensitive to ethylene eliminates both ethylene binding and the interaction of topper with the receptor. A sequence from the genome of the cyanobacterium Synechocystis sp, strain 6803 that shows homology to the ethylene-binding domain of ETR1 encodes a functional ethylene-binding protein. On the basis of sequence conservation between the Arabidopsis and the cyanobacterial ethylene-binding domains and on in vitro mutagenesis of ETR1, a structural model for this copper-based ethylene sensor domain is presented.

引用

页码：996 / 998

页数：3

共 21 条

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