Synthetic approaches towards phorbols via the ultra-high-pressure mediated intramolecular Diels-Alder reaction of furans (IMDAF):: effect of furan substitution

被引：22

作者：

Brickwood, AC

Drew, MGB

Harwood, LM ^{[1
]}

Ishikawa, T

Marais, P

Morisson, V

机构：

[1] Univ Reading, Dept Chem, Reading RG6 6AD, Berks, England

[2] Univ Oxford, Dyson Perrins Lab, Oxford OX1 3QY, England

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1999年 / 08期

关键词：

D O I：

10.1039/a900337a

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Tricyclic structures having the functionality and stereochemistry inherent in phorbol and its analogues may be rapidly constructed by an ultra-high pressure IMDAF reaction. The nature of the 2-thioether substituent on the furan diene is critical for the success of the key cycloaddition reaction.

引用

页码：913 / 921

页数：9

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