Self-assembled peptide tubelets with 7 Å pores

被引:63
作者
Amorín, M
Castedo, L
Granja, JR [1 ]
机构
[1] Univ Santiago, Dept Quim Organ, Santiago De Compostela 15782, Spain
[2] Univ Santiago, Fac Quim, CSIC, Unidad Asociada, Santiago De Compostela 15782, Spain
关键词
amino acids; dimerization; nanotubes; peptides; self-assembly;
D O I
10.1002/chem.200500478
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Here we report the preparation and structural characteristics of self-as sembling peptide tubelets composed of 32-membered rings formed of alternating a-amino acids and cis-3-aminocyclohexanecarboxylic acids. The tubelets possess a partial hydrophobic core environment, provided by the projection of the cyclohexane C2 methylene moiety into the lumen, and a Van der Waals pore diameter of about 7 (A) over circle.
引用
收藏
页码:6543 / 6551
页数:9
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