Molecular networks: The top-down view

被引：139

作者：

Bray, D ^{[1
]}

机构：

[1] Univ Cambridge, Dept Zool, Cambridge CB2 3EJ, England

来源：

SCIENCE | 2003年 / 301卷 / 5641期

关键词：

D O I：

10.1126/science.1089118

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Network theory can give a useful overview of how a biological system works. But to make testable predictions, we need the details.

引用

页码：1864 / 1865

页数：2

共 15 条

[1] Biological networks: The tinkerer as an engineer [J].

Alon, U .

SCIENCE, 2003, 301 (5641) :1866-1867

[2]

Barabasi A.L., 2002, The formula: the universal laws of success

[3] Emergent properties of networks of biological signaling pathways [J].

Bhalla, US ;

Iyengar, R .

SCIENCE, 1999, 283 (5400) :381-387

[4] PROTEIN MOLECULES AS COMPUTATIONAL ELEMENTS IN LIVING CELLS [J].

BRAY, D .

NATURE, 1995, 376 (6538) :307-312

[5] A genomic regulatory network for development [J].

Davidson, EH ;

Rast, JP ;

Oliveri, P ;

Ransick, A ;

Calestani, C ;

Yuh, CH ;

Minokawa, T ;

Amore, G ;

Hinman, V ;

Arenas-Mena, C ;

Otim, O ;

Brown, CT ;

Livi, CB ;

Lee, PY ;

Revilla, R ;

Rust, AG ;

Pan, ZJ ;

Schilstra, MJ ;

Clarke, PJC ;

Arnone, MI ;

Rowen, L ;

Cameron, RA ;

McClay, DR ;

Hood, L ;

Bolouri, H .

SCIENCE, 2002, 295 (5560) :1669-1678

[6]

Fell D., 1997, Understanding the control of metabolism

[7] HOW NEURAL NETWORKS LEARN FROM EXPERIENCE [J].

HINTON, GE .

SCIENTIFIC AMERICAN, 1992, 267 (03) :145-151

[8] Lethality and centrality in protein networks [J].

Jeong, H ;

Mason, SP ;

Barabási, AL ;

Oltvai, ZN .

NATURE, 2001, 411 (6833) :41-42

[9]

KACSER H, 1973, S SOC EXP BIOL, V32, P65

[10] METABOLIC STABILITY AND EPIGENESIS IN RANDOMLY CONSTRUCTED GENETIC NETS [J].

KAUFFMAN, SA .

JOURNAL OF THEORETICAL BIOLOGY, 1969, 22 (03) :437-&

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