Lipid carriers: A versatile delivery vehicle for proteins and peptides

被引：77

作者：

Rawat, Manju ^{[1
]}

Singh, Deependra ^{[1
]}

Saraf, S. ^{[1
]}

Saraf, Swarnlata ^{[1
]}

机构：

[1] Pt Ravishankar Shukla Univ, Inst Pharm, Raipur 492010, Madhya Pradesh, India

来源：

YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN | 2008年 / 128卷 / 02期

关键词：

lipid; protein; peptide; delivery system;

D O I：

10.1248/yakushi.128.269

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Lipid based carriers have attracted increasing scientific and commercial attention during the last few years as an alternative material for the delivery of peptides and proteins concerned with stability issues. This article presents an overview of different types of biocompatible and versatile lipid-based carriers employed for the delivery of therapeutic proteins and peptides. Such delivery systems are discussed and exemplified regarding both more traditional lipid based delivery systems such as liposomes and lipid emulsions as well as more novel structures, e.g., lipid microtubules, microbubbles, and solid lipid nanoparticles.

引用

页码：269 / 280

页数：12

共 102 条

[1] Liposomes - Opportunities in drug delivery [J].

Allen, TM .

DRUGS, 1997, 54 (Suppl 4) :8-14

[2] Peptide-loaded solid lipid nanoparticles (SLN): Influence of production parameters [J].

Almeida, AJ ;

Runge, S ;

Muller, RH .

INTERNATIONAL JOURNAL OF PHARMACEUTICS, 1997, 149 (02) :255-265

[3]

AMSELEM S, 1992, VACCINE RES, V1, P383

[4]

AMSELEM S, 1996, DRUGS PHARM SCI, V77, P149

[5]

[Anonymous], 2005, TRANSDERMAL TOPICAL, DOI DOI 10.1201/9781420039832

[6]

[Anonymous], 1998, EUROCOSMETICS

[7] SOLID LIPOSPHERES OBTAINED FROM HOT MICROEMULSIONS IN THE PRESENCE OF DIFFERENT CONCENTRATIONS OF COSURFACTANT - THE CRYSTALLIZATION OF STEARIC-ACID POLYMORPHS [J].

AQUILANO, D ;

CAVALLI, R ;

GASCO, MR .

THERMOCHIMICA ACTA, 1993, 230 :29-37

[8] Augmentation of cardiac protein delivery using ultrasound targeted microbubble destruction [J].

Bekeredjian, R ;

Chen, SY ;

Grayburn, PA ;

Shohet, RV .

ULTRASOUND IN MEDICINE AND BIOLOGY, 2005, 31 (05) :687-691

[9] Cyclosporin nanoparticulate lipospheres for oral administration [J].

Bekerman, T ;

Golenser, J ;

Domb, A .

JOURNAL OF PHARMACEUTICAL SCIENCES, 2004, 93 (05) :1264-1270

[10] INTERLEUKIN-2-CONTAINING LIPOSOMES - INTERACTION OF INTERLEUKIN-2 WITH LIPOSOMAL BILAYERS AND PRELIMINARY STUDIES ON APPLICATION IN CANCER VACCINES [J].

BERGERS, JJ ;

DENOTTER, W ;

DULLENS, HFJ ;

KERKVLIET, CTM ;

CROMMELIN, DJA .

PHARMACEUTICAL RESEARCH, 1993, 10 (12) :1715-1721

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