Lipid carriers: A versatile delivery vehicle for proteins and peptides

被引:77
作者
Rawat, Manju [1 ]
Singh, Deependra [1 ]
Saraf, S. [1 ]
Saraf, Swarnlata [1 ]
机构
[1] Pt Ravishankar Shukla Univ, Inst Pharm, Raipur 492010, Madhya Pradesh, India
来源
YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN | 2008年 / 128卷 / 02期
关键词
lipid; protein; peptide; delivery system;
D O I
10.1248/yakushi.128.269
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Lipid based carriers have attracted increasing scientific and commercial attention during the last few years as an alternative material for the delivery of peptides and proteins concerned with stability issues. This article presents an overview of different types of biocompatible and versatile lipid-based carriers employed for the delivery of therapeutic proteins and peptides. Such delivery systems are discussed and exemplified regarding both more traditional lipid based delivery systems such as liposomes and lipid emulsions as well as more novel structures, e.g., lipid microtubules, microbubbles, and solid lipid nanoparticles.
引用
收藏
页码:269 / 280
页数:12
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