A SAW immunosensor for operation in liquid using a SiO2 protective layer

被引:54
作者
Freudenberg, J [1 ]
von Schickfus, M [1 ]
Hunklinger, S [1 ]
机构
[1] Univ Heidelberg, Kirchhoff Inst Phys, D-69120 Heidelberg, Germany
关键词
surface acoustic wave; love wave; inductive coupling; immunosensor; liquid sensor;
D O I
10.1016/S0925-4005(01)00610-4
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
The key to accessing the full potential of surface acoustic wave (SAW) sensors in liquid environments lies in a protection of the necessary electrode structures. In this work, we present a combination of a SiO2 protective layer on LiTaO3 substrate and an inductively coupled SAW device. For efficient insulation, the layer thickness has to be of the order of the acoustic wavelength. Thus, perturbation of the acoustic surface wave occurs and therefore the influence of the protective layer thickness on the acoustic wave parameters has been calculated. By choosing a suitable layer thickness, successful application in aqueous solutions is possible. As a promising application immunosensing capabilities are demonstrated. (C) 2001 Elsevier Science B.V. All rights reserved.
引用
收藏
页码:147 / 151
页数:5
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