Multiple Ebola virus transmission events and rapid decline of central African wildlife

被引：454

作者：

Leroy, EM

Rouquet, P

Formenty, P

Souquière, S

Kilbourne, A

Froment, JM

Bermejo, M

Smit, S

Karesh, W

Swanepoel, R

Zaki, SR

Rollin, PE

机构：

[1] Ctr Int Rech Med Franceville, UR034, Inst Rech Dev, Franceville, Gabon

[2] WHO, Dept Communicable Dis Surveillance & Response, Global Alert & Response Team, Geneva, Switzerland

[3] Wildlife Conservat Soc, Bronx, NY 10460 USA

[4] Programme Conservat & Utilisat Rat Ecosyst Forest, Libreville, Gabon

[5] Natl Inst Communicable Dis, Special Pathogens Unit, ZA-2131 Johannesburg, South Africa

[6] Ctr Dis Control & Prevent, Special Pathogens Branch, Atlanta, GA 30333 USA

来源：

SCIENCE | 2004年 / 303卷 / 5656期

关键词：

D O I：

10.1126/science.1092528

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Several human and animal Ebola outbreaks have occurred over the past 4 years in Gabon and the Republic of Congo. The human outbreaks consisted of multiple simultaneous epidemics caused by different viral strains, and each epidemic resulted from the handling of a distinct gorilla, chimpanzee, or duiker carcass. These animal populations declined markedly during human Ebola outbreaks, apparently as a result of Ebola infection. Recovered carcasses were infected by a variety of Ebola strains, suggesting that Ebola outbreaks in great apes result from multiple virus introductions from the natural host. Surveillance of animal mortality may help to predict and prevent human Ebola outbreaks.

引用

页码：387 / 390

页数：4

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