Liver glutathione content and glutathione-dependent enzymes of two species of freshwater fish as bioindicators of chemical pollution

被引：69

作者：

Almar, M ^{[1
]}

Otero, L ^{[1
]}

Santos, C ^{[1
]}

González-Gallego, J ^{[1
]}

机构：

[1] Univ Leon, Dept Physiol Pharmacol & Toxicol, Leon 24071, Spain

来源：

JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH PART B-PESTICIDES FOOD CONTAMINANTS AND AGRICULTURAL WASTES | 1998年 / 33卷 / 06期

关键词：

fish; glutathione system; effluent; glutathione peroxidase; glutathione S-transferase; glutathione reductase;

D O I：

10.1080/03601239809373177

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

Glutathione content and glutahione-dependent enzymes were measured in the liver of two fish species, gudgeon (Gobio gobio) and roach (Rutilus arcasii), from the river Bernesga (Spain) caught downstream and upstream of the waste site of several chemical industries. Animals from contaminated sites display a reduced glutathione concentration and a tendency to the decrease of glutathione S-transferase activity. Glutathione peroxidase activity was significantly elevated only in the liver of Gobio gobio and glutathione reductase activity in that of Rutilus arcasii. Our data indicate that the glutathione system constitutes a sensitive biochemical indicator of chemical pollution. Relative changes of glutathione and glutathione-dependent enzymes in both fish species suggest a different susceptibility to toxins.

引用

页码：769 / 783

页数：15

共 38 条

[31] ORGANIC HYDROPEROXIDE-INDUCED LIPID-PEROXIDATION AND CELL-DEATH IN ISOLATED HEPATOCYTES [J].