Simple and chemoselective reduction of aromatic nitro compounds to aromatic amines: reduction with hydriodic acid revisited

被引：69

作者：

Kumar, JSD ^{[1
]}

Ho, MM ^{[1
]}

Toyokuni, T ^{[1
]}

机构：

[1] Univ Calif Los Angeles, Sch Med, Dept Mol & Med Pharmacol, Crump Inst Mol Imaging, Los Angeles, CA 90095 USA

来源：

TETRAHEDRON LETTERS | 2001年 / 42卷 / 33期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1016/S0040-4039(01)01083-8

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Reduction of aromatic nitro compounds to amines with hydriodic acid as reinvestigated. Under a milder non-refluxing condition (at 90 degreesC for 2 4 h), the reduction proceeded efficiently with excellent chemoselectivity without affecting other functional groups including nitrile, ester, halide, carbonyl, amide, Sulfonamide, imidazole and methylthio groups. (C) 2001 Elsevier Science Ltd. All rights reserved.

引用

页码：5601 / 5603

页数：3

共 21 条

[1] Selective reductions of nitroarenes to anilines using metallic zinc in near-critical water [J].