Boosting p53 with interferon and viruses

被引：27

作者：

Vilcek, J ^{[1
]}

机构：

[1] NYU, Sch Med, New York, NY 10010 USA

来源：

NATURE IMMUNOLOGY | 2003年 / 4卷 / 09期

关键词：

D O I：

10.1038/ni0903-825

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Interferon-alpha/beta proteins are vital for innate immune responses to viruses. The tumor suppressor p53 mediates cell cycle arrest and apoptosis. A recent study in Nature reports that interferon-alpha/beta stimulates p53 synthesis, demonstrating a hitherto unrecognized link.

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页码：825 / 826

页数：2

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