Screening for Antimicrobial Resistance Genes and Virulence Factors via Genome Sequencing

被引:38
作者
Bennedsen, Mads [1 ]
Stuer-Lauridsen, Birgitte [1 ]
Danielsen, Morten [1 ]
Johansen, Eric [1 ]
机构
[1] Chr Hansen AS, Innovat, DK-2970 Horsholm, Denmark
关键词
D O I
10.1128/AEM.02493-10
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Second-generation genome sequencing and alignment of the resulting reads to in silico genomes containing antimicrobial resistance and virulence factor genes were used to screen for undesirable genes in 28 strains which could be used in human nutrition. No virulence factor genes were detected, while several isolates contained antimicrobial resistance genes.
引用
收藏
页码:2785 / 2787
页数:3
相关论文
共 15 条
[11]  
Sanders M., 2009, Functional Food Rev, V1, P3, DOI DOI 10.2310/6180.2009.00002
[12]  
SCANLON S, 2007, THESIS U COPENHAGEN
[13]   Biosafety assessment of probiotics used for human consumption: recommendations from the EU-PROSAFE project [J].
Vankerckhoven, Vanessa ;
Huys, Geert ;
Vancanneyt, Marc ;
Vael, Carl ;
Klare, Ingo ;
Romond, Marie-Benedicte ;
Entenza, Jose M. ;
Moreillon, Philippe ;
Wind, Richele D. ;
Knol, Jan ;
Wiertz, Emmanuel ;
Pot, Bruno ;
Vaughan, Elaine E. ;
Kahlmeter, Gunnar ;
Goossens, Herman .
TRENDS IN FOOD SCIENCE & TECHNOLOGY, 2008, 19 (02) :102-114
[14]   Database resources of the national center for biotechnology information [J].
Wheeler, David L. ;
Barrett, Tanya ;
Benson, Dennis A. ;
Bryant, Stephen H. ;
Canese, Kathi ;
Chetvernin, Vyacheslav ;
Church, Deanna M. ;
DiCuccio, Michael ;
Edgar, Ron ;
Federhen, Scott ;
Feolo, Michael ;
Geer, Lewis Y. ;
Helmberg, Wolfgang ;
Kapustin, Yuri ;
Khovayko, Oleg ;
Landsman, David ;
Lipman, David J. ;
Madden, Thomas L. ;
Maglott, Donna R. ;
Miller, Vadim ;
Ostell, James ;
Pruitt, Kim D. ;
Schuler, Gregory D. ;
Shumway, Martin ;
Sequeira, Edwin ;
Sherry, Steven T. ;
Sirotkin, Karl ;
Souvorov, Alexandre ;
Starchenko, Grigory ;
Tatusov, Roman L. ;
Tatusova, Tatiana A. ;
Wagner, Lukas ;
Yaschenko, Eugene .
NUCLEIC ACIDS RESEARCH, 2008, 36 :D13-D21
[15]   VFDB 2008 release: an enhanced web-based resource for comparative pathogenomics [J].
Yang, Jian ;
Chen, Lihong ;
Sun, Lilian ;
Yu, Jun ;
Jin, Qi .
NUCLEIC ACIDS RESEARCH, 2008, 36 :D539-D542