ALFRED: an allele frequency database for diverse populations and DNA polymorphism - an update

被引:33
作者
Osier, MV
Cheung, KH
Kidd, JR
Pakstis, AJ
Miller, PL
Kidd, KK
机构
[1] Yale Univ, Sch Med, Dept Genet, New Haven, CT 06520 USA
[2] Yale Univ, Sch Med, Ctr Med Informat, New Haven, CT 06520 USA
关键词
D O I
10.1093/nar/29.1.317
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
ALFRED (the ALelle FREquency Database) is designed to store and disseminate frequencies of alleles at human polymorphic sites for multiple populations, primarily for the population genetics and molecular anthropology communities. Currently ALFRED has information on over 180 polymorphic sites for more than 70 populations. Since our initial release of the database we have focussed on increasing the quantity and quality of data, making reciprocal links between ALFRED and other related databases, and providing useful tools to make the data more comprehensible to the end user. ALFRED is accessible from the Kidd Lab home page (http://info.med.yale.edu/genetics/kkidd/) or from ALFRED directly (http://alfred.med.yale.edu/alfred/ index.asp).
引用
收藏
页码:317 / 319
页数:3
相关论文
共 13 条
[1]   HGBASE:: a database of SNPs and other variations in and around human genes [J].
Brookes, AJ ;
Lehväslaiho, H ;
Siegfried, M ;
Boehm, JG ;
Yuan, YP ;
Sarkar, CM ;
Bork, P ;
Ortigao, F .
NUCLEIC ACIDS RESEARCH, 2000, 28 (01) :356-360
[2]   Short tandem repeat polymorphism evolution in humans [J].
Calafell, F ;
Shuster, A ;
Speed, WC ;
Kidd, JR ;
Kidd, KK .
EUROPEAN JOURNAL OF HUMAN GENETICS, 1998, 6 (01) :38-49
[3]   Characterization of single-nucleotide polymorphisms in coding regions of human genes [J].
Cargill, M ;
Altshuler, D ;
Ireland, J ;
Sklar, P ;
Ardlie, K ;
Patil, N ;
Lane, CR ;
Lim, EP ;
Kalyanaraman, N ;
Nemesh, J ;
Ziaugra, L ;
Friedland, L ;
Rolfe, A ;
Warrington, J ;
Lipshutz, R ;
Daley, GQ ;
Lander, ES .
NATURE GENETICS, 1999, 22 (03) :231-238
[4]  
Cheung K H, 2000, Pac Symp Biocomput, P639
[5]   ALFRED: an allele frequency database for diverse populations and DNA polymorphisms [J].
Cheung, KH ;
Osier, MV ;
Kidd, JR ;
Pakstis, AJ ;
Miller, PL ;
Kidd, KK .
NUCLEIC ACIDS RESEARCH, 2000, 28 (01) :361-363
[6]   Linkage disequilibrium and allele-frequency distributions for 114 single-nucleotide polymorphisms in five populations [J].
Goddard, KAB ;
Hopkins, PJ ;
Hall, JM ;
Witte, JS .
AMERICAN JOURNAL OF HUMAN GENETICS, 2000, 66 (01) :216-234
[7]  
GRIMES BF, 1996, ETHNOLOGUE LANGUAGES, P966
[8]   Haplotypes and linkage disequilibrium at the phenylalanine hydroxylase locus, PAH, in a global representation of populations [J].
Kidd, JR ;
Pakstis, AJ ;
Zhao, HY ;
Lu, RB ;
Okonofua, FE ;
Odunsi, A ;
Grigorenko, E ;
Bonne-Tamir, B ;
Friedlaender, J ;
Schulz, LO ;
Parnas, J ;
Kidd, KK .
AMERICAN JOURNAL OF HUMAN GENETICS, 2000, 66 (06) :1882-1899
[9]   dbSNP: the NCBI database of genetic variation [J].
Sherry, ST ;
Ward, MH ;
Kholodov, M ;
Baker, J ;
Phan, L ;
Smigielski, EM ;
Sirotkin, K .
NUCLEIC ACIDS RESEARCH, 2001, 29 (01) :308-311
[10]   dbSNP: a database of single nucleotide polymorphisms [J].
Smigielski, EM ;
Sirotkin, K ;
Ward, M ;
Sherry, ST .
NUCLEIC ACIDS RESEARCH, 2000, 28 (01) :352-355