dbSNP: a database of single nucleotide polymorphisms

In response to a need for a general catalog of genome variation to address the large-scale sampling designs required by association studies, gene mapping and evolutionary biology, the National Cancer for Biotechnology Information (NCBI) has established the dbSNP database. Submissions to dbSNP will be integrated with other sources of information at NCBI such as GenBank, PubMed, LocusLink and the Human Genome Project data, The complete contents of dbSNP are available to the public at website:http://www.ncbi.nlm.nih.gov/SNP, Submitted SNPs can also be downloaded via anonymous FTP at ftp://ncbi. nlm.nih.gov/snp/.