Characterisation of the transition states for protein folding: towards a new level of mechanistic detail in protein engineering analysis

被引：92

作者：

Oliveberg, M ^{[1
]}

机构：

[1] Umea Univ, S-90187 Umea, Sweden

来源：

CURRENT OPINION IN STRUCTURAL BIOLOGY | 2001年 / 11卷 / 01期

关键词：

D O I：

10.1016/S0959-440X(00)00171-8

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The field of protein folding now offers considerable excitement. Comparative studies of the transition-state structures for a series of protein families with analogous structures have helped to uncover the overall rules for protein folding. In addition, new protein engineering experiments that continuously follow the growth of the folding nucleus have started to fill in the missing details.

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页码：94 / 100

页数：7

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