Trading translation with RNA-binding proteins

被引：46

作者：

Abaza, Irina ^{[1
]}

Gebauer, Fatima ^{[1
]}

机构：

[1] CRG, Gene Regulat Programme, Barcelona 08003, Spain

来源：

RNA | 2008年 / 14卷 / 03期

关键词：

translation; RNA-binding proteins; hnRNP K; SXL; Maskin; cup; IRP; GAIT; CPEB; Smaug;

D O I：

10.1261/rna.848208

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

RNA-binding proteins regulate every aspect of RNA metabolism, including pre-mRNA splicing, mRNA trafficking, stability, and translation. This review summarizes the available information on molecular mechanisms of translational repression by RNA-binding proteins. By using a specific set of well-defined examples, we also describe how regulation can be reversed.

引用

页码：404 / 409

页数：6