Anti-anaerobic activity of levofloxacin alone and combined with clindamycin and metronidazole

被引：11

作者：

Credito, KL

Jacobs, MR

Appelbaum, PC

机构：

[1] Milton S Hershey Med Ctr, Dept Pathol, Hershey, PA 17033 USA

[2] Milton S Hershey Med Ctr, Dept Clin Microbiol, Hershey, PA 17033 USA

[3] Case Western Reserve Univ, Cleveland, OH 44106 USA

来源：

DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE | 2000年 / 38卷 / 03期

关键词：

D O I：

10.1016/S0732-8893(00)00190-5

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Microdilution MICs of levofloxacin against twelve anaerobes ranged between 0.5-8.0 mug/ml and those of clindamycin and metronidazole between 0.008-2.0 and 0.25->16.0 mug/ml, respectively. Combination of levofloxacin with clindamycin and/or metronidazole in time-kill tests led to synergy at levofloxacin concentrations at or below the MIC in 7/12 strains. (C) 2000 Elsevier Science Inc. All rights reserved.

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页码：181 / 183

页数：3

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