Strategies for the use of mixture-based synthetic combinatorial libraries: Scaffold ranking, direct testing, in vivo, and enhanced deconvolution by computational methods

被引：98

作者：

Houghten, Richard A. ^{[1
]}

Pinilla, Clernencia ^{[1
]}

Giulianotti, Marc A. ^{[1
]}

Appel, Jon R. ^{[1
]}

Dooley, Colette T. ^{[1
]}

Nefzi, Adel ^{[1
]}

Ostresh, John M. ^{[1
]}

Yu, Yongping ^{[1
]}

Maggiora, Gerald M. ^{[2
]}

Medina-Franco, Jose L. ^{[2
]}

Brunner, Daniela ^{[3
]}

Schneider, Jeff ^{[3
,4
]}

机构：

[1] Torrey Pines Inst Mol Studies, San Diego, CA 92121 USA

[2] Univ Arizona, BIO5 Inst & Coll Pharm, Tucson, AZ 85721 USA

[3] PsychoGen Inc, Tarrytown, NY 10591 USA

[4] Carnegie Mellon Univ, Sch Comp Sci, Pittsburgh, PA 15213 USA

来源：

JOURNAL OF COMBINATORIAL CHEMISTRY | 2008年 / 10卷 / 01期

关键词：

D O I：

10.1021/cc7001205

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

[No abstract available]

引用

页码：3 / 19

页数：17

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