The association between early life adversity and bacterial vaginosis during pregnancy

被引：31

作者：

Cammack, Alison L. ^{[5
]}

Buss, Claudia

Entringer, Sonja

Hogue, Carol J. ^{[5
]}

Hobel, Calvin J. ^{[4
]}

Wadhwa, Pathik D. ^{[1
,2
,3
]}

机构：

[1] Univ Calif Irvine, UC Irvine Dev Hlth & Dis Res Program, Sch Med, Dept Psychiat & Human Behav,Gillespie Neurosci Re, Irvine, CA 92697 USA

[2] Univ Calif Irvine, Sch Med, Dept Obstet & Gynecol, Irvine, CA 92697 USA

[3] Univ Calif Irvine, Sch Med, Dept Pediat, Irvine, CA 92697 USA

[4] Cedars Sinai Med Ctr, Dept Obstet & Gynecol, Div Maternal Fetal Med, Los Angeles, CA 90048 USA

[5] Emory Univ, Dept Epidemiol, Rollins Sch Publ Hlth, Atlanta, GA 30322 USA

来源：

AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY | 2011年 / 204卷 / 05期

基金：

美国国家卫生研究院;

关键词：

bacterial vaginosis; child abuse; life course; pregnancy; psychosocial stress; CHILDHOOD SEXUAL-ABUSE; PSYCHOSOCIAL STRESS; PRETERM DELIVERY; PERCEIVED DISCRIMINATION; SOCIOECONOMIC-STATUS; DEPRESSIVE SYMPTOMS; RACIAL-DIFFERENCES; WOMEN; BIRTH; RISK;

D O I：

10.1016/j.ajog.2011.01.054

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

OBJECTIVE: The purpose of this study was to examine associations between chronic preconception psychosocial and socioeconomic stress with bacterial vaginosis (BV) during pregnancy. STUDY DESIGN: Using univariate and multivariate logistic regression, childhood abuse and neglect, chronic discrimination, childhood socioeconomic status, potential confounders, and BV were assessed at 14-16 and 19-22 weeks' gestation in a cohort of 312 pregnant women. RESULTS: Persistent BV (BV positive at both time points vs no BV at either time point) was associated with childhood sexual abuse (CSA), chronic discrimination, and lack of parental home ownership. These associations were still present after covarying for current perceived stress, socioeconomic status, and other potential confounders. CONCLUSION: There is evidence that BV during pregnancy is independently linked with early life psychosocial adversity, suggesting that a life-course perspective may be important in elucidating determinants of perinatal outcomes.

引用

页码：431.e1 / 431.e8

页数：8