Spiroimidazolidinone library derivatives on SynPhase lanterns

被引：13

作者：

Feliu, L ^{[1
]}

Subra, G ^{[1
]}

Martinez, J ^{[1
]}

Amblard, M ^{[1
]}

机构：

[1] Fac Pharm Montpellier, Lab Amino Acides Peptides & Prot, CNRS, UMR 5810, F-34000 Montpellier, France

来源：

JOURNAL OF COMBINATORIAL CHEMISTRY | 2003年 / 5卷 / 04期

关键词：

D O I：

10.1021/cc020111p

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

Optimization and solid-phase synthesis of new spiroimidazolidinone derivatives as highly functionalized templates is reported. The synthesis of 1,4,8-triazaspiro[4.5] decan-2-one derivatives was performed on SynPhase lanterns from dipeptides anchored on the solid support and N-protected piperidone. A library of 180 discrete compounds was prepared.

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页码：356 / 361

页数：6

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