Relations between the neural bases of dynamic auditory processing and phonological processing: Evidence from fMRI

被引:202
作者
Poldrack, RA
Temple, E
Protopapas, A
Nagarajan, S
Tallal, P
Merzenich, M
Gabrieli, JDE
机构
[1] MGH NMR Ctr, Charlestown, MA 02129 USA
[2] Harvard Univ, Sch Med, Cambridge, MA 02138 USA
[3] Stanford Univ, Stanford, CA 94305 USA
[4] Sci Learning Corp, Berkeley, CA USA
[5] Univ Calif Berkeley, Berkeley, CA 94720 USA
[6] Rutgers State Univ, Piscataway, NJ 08855 USA
关键词
D O I
10.1162/089892901750363235
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Functional magnetic resonance imaging (fMRI) was used to examine how the brain responds ri, temporal compression of speech and to determine whether the same regions are also involved in phonological processes associated with reading. Recorded speech was temporally compressed to varying degrees anti presented in a sentence verification task. Regions involved in phonological processing were identified in a separate scan using a rhyming judgment task with pseudo-words compared to a lettercase judgment task. The left inferior frontal and left superior temporal regions (Broca's and Wernicke's areas), along with the right inferior frontal cortex. demonstrated a convex response to speech compression; their activity increased as compression increased, but then decreased when speech became incomprehensible. Other regions exhibited linear increases in activity as compression increased, including the middle frontal gyri bilaterally. The auditory cortices exhibited compression-related decreases bilaterally, primarily reflecting a decrease in activity when speech became incomprehensible. Rhyme judgments engaged two left inferior frontal gyrus regions (pars triangularis and pars opercularis), of which only the pars triangularis region exhibited significant compression-related activity. These results directly demonstrate that a subset of the left inferior frontal regions involved in phonological processing is also sensitive to transient acoustic features within the range of comprehensible speech.
引用
收藏
页码:687 / 697
页数:11
相关论文
共 66 条
[1]   Auditory processing parallels reading abilities in adults [J].
Ahissar, M ;
Protopapas, A ;
Reid, M ;
Merzenich, MM .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2000, 97 (12) :6832-6837
[2]   A distributed cortical network for auditory sensory memory in humans [J].
Alain, C ;
Woods, DL ;
Knight, RT .
BRAIN RESEARCH, 1998, 812 (1-2) :23-37
[3]   BINOMIAL DISTRIBUTION OF RIGHT MIXED AND LEFT HANDEDNESS [J].
ANNETT, M .
QUARTERLY JOURNAL OF EXPERIMENTAL PSYCHOLOGY, 1967, 19 :327-&
[4]   PURE WORD DEAFNESS - ANALYSIS OF A CASE WITH BILATERAL LESIONS AND A DEFECT AT THE PRE-PHONEMIC LEVEL [J].
AUERBACH, SH ;
ALLARD, T ;
NAESER, M ;
ALEXANDER, MP ;
ALBERT, ML .
BRAIN, 1982, 105 (JUN) :271-300
[5]   PROPERTIES AND DISTRIBUTION OF AUDITORY NEURONS IN THE DORSOLATERAL PREFRONTAL CORTEX OF THE ALERT MONKEY [J].
AZUMA, M ;
SUZUKI, H .
BRAIN RESEARCH, 1984, 298 (02) :343-346
[6]   Functional MRI of brain activation induced by scanner acoustic noise [J].
Bandettini, PA ;
Jesmanowicz, A ;
Van Kylen, J ;
Birn, RM ;
Hyde, JS .
MAGNETIC RESONANCE IN MEDICINE, 1998, 39 (03) :410-416
[7]   Lateralization of speech and auditory temporal processing [J].
Belin, P ;
Zilbovicius, M ;
Crozier, S ;
Thivard, L ;
Fontaine, A .
JOURNAL OF COGNITIVE NEUROSCIENCE, 1998, 10 (04) :536-540
[8]   Auditory temporal processing thresholds, habituation, and recognition memory over the 1st year [J].
Benasich, AA ;
Tallal, P .
INFANT BEHAVIOR & DEVELOPMENT, 1996, 19 (03) :339-357
[9]   FUNCTIONAL MAGNETIC-RESONANCE-IMAGING OF HUMAN AUDITORY-CORTEX [J].
BINDER, JR ;
RAO, SM ;
HAMMEKE, TA ;
YETKIN, FZ ;
JESMANOWICZ, A ;
BANDETTINI, PA ;
WONG, EC ;
ESTKOWSKI, LD ;
GOLDSTEIN, MD ;
HAUGHTON, VM ;
HYDE, JS .
ANNALS OF NEUROLOGY, 1994, 35 (06) :662-672
[10]   IMPAIRMENTS OF SPEECH PRODUCTION AND SPEECH-PERCEPTION IN APHASIA [J].
BLUMSTEIN, SE .
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES, 1994, 346 (1315) :29-36