Resolving the genetics of resistance to infectious diseases

被引:14
作者
Hawken, RJ [1 ]
Beattie, CW [1 ]
Schook, LB [1 ]
机构
[1] Univ Minnesota, Coll Vet Med, Program Comparat Genom, Food Anim Biotechnol Ctr, St Paul, MN 55108 USA
来源
REVUE SCIENTIFIQUE ET TECHNIQUE-OFFICE INTERNATIONAL DES EPIZOOTIES | 1998年 / 17卷 / 01期
关键词
animal diseases; disease resistance; genetics; susceptibility;
D O I
10.20506/rst.17.1.1098
中图分类号
S85 [动物医学(兽医学)];
学科分类号
0906 ;
摘要
The genetics of resistance to disease is an area of great interest in agriculturally important plant and animal species. Selective breeding for resistance to pathogens in plants, animals and insects has demonstrated that resistance and susceptibility to pathogens are controlled by both genetic and environmental factors. The immune loci causally involved in susceptibility and resistance to disease are currently unknown. However, novel enabling molecular technologies promise to assist in unravelling the genetics of the host response to infectious diseases in new ways, and ultimately to improve seed stock genetics.
引用
收藏
页码:17 / 25
页数:9
相关论文
共 75 条
[41]  
LEWIN HA, 1991, GENE MAPPING TECHNIQ, P283
[42]   Antibody response to Actinobacillus pleuropneumoniae antigens after vaccination of pigs bred for high and low immune response [J].
Magnusson, U ;
Bosse, J ;
Mallard, BA ;
Rosendal, S ;
Wilkie, BN .
VACCINE, 1997, 15 (09) :997-1000
[43]  
Mallard B. A., 1992, Animal Biotechnology, V3, P257, DOI 10.1080/10495399209525776
[44]  
Mallard B. A., 1993, Veterinary Immunology and Immunopathology, V38, P392
[45]   GENETIC-CONTROL OF HOST-RESISTANCE TO INFECTION [J].
MALO, D ;
SKAMENE, E .
TRENDS IN GENETICS, 1994, 10 (10) :365-371
[46]   VIRUS-SPECIFIC CTL IN SLA-INBRED SWINE RECOVERED FROM EXPERIMENTAL AFRICAN SWINE FEVER VIRUS (ASFV) INFECTION [J].
MARTINS, C ;
MEBUS, C ;
SCHOLL, T ;
LAWMAN, M ;
LUNNEY, J .
ANNALS OF THE NEW YORK ACADEMY OF SCIENCES, 1988, 532 :462-464
[47]   Intracellular, genetic or congenital immunisation - Transgenic approaches to increase disease resistance of farm animals [J].
Muller, M ;
Brem, G .
JOURNAL OF BIOTECHNOLOGY, 1996, 44 (1-3) :233-242
[48]   GENETIC-RESISTANCE TO AFRICAN TRYPANOSOMIASIS [J].
MURRAY, M ;
TRAIL, JCM ;
DAVIS, CE ;
BLACK, SJ .
JOURNAL OF INFECTIOUS DISEASES, 1984, 149 (03) :311-319
[49]  
NADEAU JH, 1995, J INFLAMM, V45, P27
[50]  
OBRIEN SJ, 1990, NAT GENET, V15, P47