Epidemiology of Renal Cell Cancer

被引：91

作者：

Cho, Eunyoung ^{[1
,2
,3
]}

Adami, Hans-Olov ^{[4
,5
]}

Lindblad, Per ^{[6
]}

机构：

[1] Harvard Univ, Sch Med, Channing Lab, Dept Med, Boston, MA 02115 USA

[2] Brigham & Womens Hosp, Boston, MA 02115 USA

[3] Harvard Univ, Dept Nutr, Sch Publ Hlth, Boston, MA 02115 USA

[4] Harvard Univ, Dept Epidemiol, Sch Publ Hlth, Boston, MA 02215 USA

[5] Karolinska Inst, Dept Med Epidemiol & Biostat, SE-17177 Stockholm, Sweden

[6] Orebro Univ Hosp, Dept Urol, SE-70185 Orebro, Sweden

来源：

HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA | 2011年 / 25卷 / 04期

关键词：

Renal cell cancer; Epidemiology; Risk factors; Incidence; Mortality; Smoking; Obesity; Hypertension; BODY-MASS INDEX; OCCUPATIONAL RISK-FACTORS; MODERATE ALCOHOL INTAKE; KIDNEY-CANCER; PHYSICAL-ACTIVITY; DIABETES-MELLITUS; REPRODUCTIVE FACTORS; POOLED ANALYSIS; ANTIHYPERTENSIVE MEDICATIONS; NATIONWIDE COHORT;

D O I：

10.1016/j.hoc.2011.04.002

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Renal cell cancer (RCC) is increasingly diagnosed at an early stage in many countries, which likely contributes to the recent leveling of RCC mortality in the United States and many European countries. However, over all stages nearly 50% of the patients die within 5 years after diagnosis. Smoking and obesity may account for approximately 40% of all incidental cases in high-risk countries. Besides obesity, rising prevalence of hypertension may play a growing role. Several other occupational and lifestyle factors may also affect the risk of RCC. Genetic variations may be an important factor in the differing incidence among populations.

引用

页码：651 / +

页数：16

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