Pregnane glycosides from Caralluma retrospiciens

被引：30

作者：

Halim, AF ^{[1
]}

Khalil, AT ^{[1
]}

机构：

[1] MANSOURA UNIV,FAC PHARM,MANSOURA,EGYPT

来源：

PHYTOCHEMISTRY | 1996年 / 42卷 / 04期

关键词：

Caralluma retrospiciens; asclepiadaceae; pregnane glycosides; new diacylated pregnane trioside;

D O I：

10.1016/0031-9422(96)00029-5

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Two pregnane ester glycosides were isolated and identified from the alcohol extract of the aerial parts of Caralluma retrospiciens. Their structures were established as 12 beta-benzoyloxy-20-isovaleroyloxy-8 beta,14 beta-dihydroxypregnane-3-O-[beta-D-glucopyranosyl-(1-->6)-beta-D-glucopyranosyl-(1-->4)-beta-D-(3-O-methyl-6-deoxy)galactopyranoside] (caretroside A) and the bioside 12 beta-benzoyloxy-8 beta,14 beta-dihydroxypregn-20-one-3-O-[beta-D-oleandropyranosyl-(1-->4)-beta-D-cymaropyranoside]. They were characterized through physical and chemical methods in addition to standard spectroscopic techniques especially 2D NMR (COSY, HMQC and HMBC). This is the first report of the isolation of these compounds from a natural source.

引用

页码：1135 / 1139

页数：5