The stereoselective synthesis of a key intermediate of the trinem antibiotic Sanfetrinem

被引：22

作者：

Ghiron, C ^{[1
]}

Piga, E ^{[1
]}

Rossi, T ^{[1
]}

Tamburini, B ^{[1
]}

Thomas, RJ ^{[1
]}

机构：

[1] GLAXO WELLCOME SPA,MED RES CTR,I-37135 VERONA,ITALY

来源：

TETRAHEDRON LETTERS | 1996年 / 37卷 / 22期

关键词：

D O I：

10.1016/0040-4039(96)00682-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

By modulating the reactivity of the Lewis acid promoter it was possible to obtain, in a single stereoselective condensation step, the methoxyketone 7, an advanced intermediate in the synthesis of Sanfetrinem GV104326. Copyright (C) 1996 Elsevier Science Ltd

引用

页码：3891 / 3894

页数：4

共 6 条

[1] THE SYNTHESIS OF A KEY INTERMEDIATE OF TRICYCLIC BETA-LACTAM ANTIBIOTICS
BISMARA, C
DIFABIO, R
DONATI, D
ROSSI, T
THOMAS, RJ
[J]. TETRAHEDRON LETTERS, 1995, 36 (24) : 4283 - 4286
[2] IN-VITRO ACTIVITY OF THE TRIBACTAM GV104326 AGAINST GRAM-POSITIVE, GRAM-NEGATIVE, AND ANAEROBIC-BACTERIA
DIMODUGNO, E
ERBETTI, I
FERRARI, L
GALASSI, G
HAMMOND, SM
XERRI, L
[J]. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1994, 38 (10) : 2362 - 2368
[3] REDUCTIONS OF ALPHA-SUBSTITUTED KETONES BY LITHIUM DIISOPROPYLAMIDE
KOWALSKI, C
CREARY, X
ROLLIN, AJ
BURKE, MC
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1978, 43 (13) : 2601 - 2608
[4] ROSSI L, 1995, TETRAHEDRON LETT, V35, P5285
[5] NOVEL AMIDOALKYLATION OF 4-ACETOXYAZETIDINONES WITH ALLYLIC BORANES - A STEREOSELECTIVE ENTRY INTO THE TRIBACTAMS
ROSSI, T
BIONDI, S
CONTINI, S
THOMAS, RJ
MARCHIORO, C
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1995, 117 (37) : 9604 - 9605
[6] STEAD P, IN PRESS

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