Measuring secretion in chromaffin cells using electrophysiological and electrochemical methods

被引：36

作者：

Borges, R. ^{[1
]}

Camacho, M. ^{[1
]}

Gillis, K. D. ^{[2
]}

机构：

[1] Univ La Laguna, Unidad Farmacol, Fac Med, Tenerife 38071, Spain

[2] Univ Missouri, Dalton Cardiovasc Res Ctr, Dept Med Pharmacol & Physiol, Dept Biol Engn, Columbia, MO USA

来源：

ACTA PHYSIOLOGICA | 2008年 / 192卷 / 02期

关键词：

adrenal; amperometry; catecholamine; cell capacitance; exocytosis; patch amperometry;

D O I：

10.1111/j.1748-1716.2007.01814.x

中图分类号：

Q4 [生理学];

学科分类号：

071003 ;

摘要：

Our present understanding of exocytosis of catecholamines has benefited tremendously from the arrival of single-cell electrochemical methods (amperometry and voltammetry), electrophysiological techniques (whole-cell and patch capacitance) and from the combination of both techniques (patch amperometry). In this brief review, we will outline the strengths and limitations of amperometric and electrophysiological methods and highlight the major contribution obtained with the use of these techniques in chromaffin cells.

引用

页码：173 / 184

页数：12

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