Biomaterials based on chitin and chitosan in wound dressing applications

被引：1552

作者：

Jayakumar, R. ^{[1
]}

Prabaharan, M. ^{[2
]}

Kumar, P. T. Sudheesh ^{[1
]}

Nair, S. V. ^{[1
]}

Tamura, H. ^{[3
]}

机构：

[1] Amrita Vishwa Vidhyapeetham Univ, Amrita Inst Med Sci & Res Ctr, Amrita Ctr Nanosci & Mol Med, Cochin 682041, Kerala, India

[2] SRM Univ, Fac Engn & Technol, Dept Chem, Kattankulathur 603203, India

[3] Kansai Univ, Fac Chem Mat & Bioengn, Osaka 5648680, Japan

来源：

BIOTECHNOLOGY ADVANCES | 2011年 / 29卷 / 03期

关键词：

Chitin; Chitosan; Membranes; Nanofibers; Scaffolds; Hydrogels; Sponges; Wound dressing; FIBROBLAST-GROWTH-FACTOR; WATER-SOLUBLE CHITIN; IN-VITRO; ARTIFICIAL SKIN; PHOTOCROSSLINKABLE CHITOSAN; ANTIBACTERIAL PROPERTIES; NANOFIBROUS SCAFFOLDS; TOPICAL FORMULATIONS; QUATERNIZED CHITOSAN; DEGRADATION BEHAVIOR;

D O I：

10.1016/j.biotechadv.2011.01.005

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Wound dressing is one of the most promising medical applications for chitin and chitosan. The adhesive nature of chitin and chitosan, together with their antifungal and bactericidal character, and their permeability to oxygen, is a very important property associated with the treatment of wounds and burns. Different derivatives of chitin and chitosan have been prepared for this purpose in the form of hydrogels, fibers, membranes, scaffolds and sponges. The purpose of this review is to take a closer look on the wound dressing applications of biomaterials based on chitin, chitosan and their derivatives in various forms in detail. (C) 2011 Elsevier Inc. All rights reserved.

引用

页码：322 / 337

页数：16

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