Strong ligand accelerated catalysis by an Arduengo-type carbene in copper-catalysed conjugate addition

被引：82

作者：

Fraser, PK ^{[1
]}

Woodward, S ^{[1
]}

机构：

[1] Univ Nottingham, Sch Chem, Nottingham NG7 2RD, England

来源：

TETRAHEDRON LETTERS | 2001年 / 42卷 / 14期

基金：

英国工程与自然科学研究理事会;

关键词：

enones; carbenes and carbenoids; zinc and compounds;

D O I：

10.1016/S0040-4039(01)00280-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The addition of stabilised carbene ligand:CNMesCH(2)CH(2)NMes (Mes=2,4,6-Me3C6H2) results in a dramatic rate increase in the Cu(OTf)(2)-catalysed conjugate addition of ZnEt2 to enones (OTf= triflate anion). (C) 2001 Elsevier Science Ltd. All rights reserved.

引用

页码：2747 / 2749

页数：3

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