A hypothetical protein of Streptococcus mutans is critical for biofilm formation

被引：36

作者：

Brown, TA ^{[1
]}

Ahn, SJ ^{[1
]}

Frank, RN ^{[1
]}

Chen, YYM ^{[1
]}

Lemos, JA ^{[1
]}

Burne, RA ^{[1
]}

机构：

[1] Univ Florida, Coll Dent, Dept Oral Biol, Gainesville, FL 32610 USA

来源：

INFECTION AND IMMUNITY | 2005年 / 73卷 / 05期

关键词：

D O I：

10.1128/IAI.73.5.3147-3151.2005

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Inactivation of the Smu0630 gene of Streptococcus mutans resulted in dramatic decreases in biofilm formation, regardless of the carbohydrate source. The Smu0630 protein contained numerous interesting features, including a possible signal sequence and two conserved regions of repeated sequences. Smu0630 may represent a potential target for novel therapeutics.

引用

页码：3147 / 3151

页数：5

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