IS1999 increases expression of the extended-spectrum β-lactamase VEB-1 in Pseudomonas aeruginosa

被引：23

作者：

Aubert, D ^{[1
]}

Naas, T ^{[1
]}

Nordmann, P ^{[1
]}

机构：

[1] Hop Bicetre, Assistance Publ Hop Paris, Serv Bacteriol Virol, Fac Med Paris Sud, F-94275 Le Kremlin Bicetre, France

来源：

JOURNAL OF BACTERIOLOGY | 2003年 / 185卷 / 17期

关键词：

D O I：

10.1128/JB.185.17.5314-5319.2003

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The integron-borne bla(VEB-1) gene encodes an extended-spectrum beta-lactamase. This gene was associated mostly with IS1999 and rarely with an additional IS2000 element in Pseudomonas aeruginosa isolates from Thailand, whereas IS1999 was only very rarely associated with bla(VEB-1) in Enterobactetiaceae. Expression experiments and promoter study identified promoter sequences in IS1999 that increased the expression of VEB-1 in P. aeruginosa.

引用

页码：5314 / 5319

页数：6

共 18 条

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