Enantioselective Michael addition of nitromethane to α,β-enones catalyzed by chiral quaternary ammonium salts.: A simple synthesis of (R)-baclofen

被引：204

作者：

Corey, EJ ^{[1
]}

Zhang, FY ^{[1
]}

机构：

[1] Harvard Univ, Dept Chem & Chem Biol, Cambridge, MA 02138 USA

来源：

ORGANIC LETTERS | 2000年 / 2卷 / 26期

关键词：

D O I：

10.1021/ol0068344

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHICS] Enantioselective Michael addition of nitromethane to an alpha,beta -enone is a key step in the synthesis of (R) baclofen.

引用

页码：4257 / 4259

页数：3

共 21 条

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